Bleeding after Taking Dual Antiplatelets and NSAID Concurrently
نویسندگان
چکیده
منابع مشابه
Commentary: risk factors for gastrointestinal bleeding in NSAID users.
SIRS, We thank Dr Hawkey for his interest in our article 2 and agree with some of his comments concerning the limitations of the study. In our article and in the original publication of the CONDOR trial, we clearly stated that the most frequent outcome event was a decrease in haemoglobin (Hb) 2g/dL of presumed small bowel origin. The adjudication of the events was based on a rigorous protocol, ...
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We present a 55 years old male with severe anemia with history of pain abdomen for 2 weeks and malena of 10 days duration. He was taking NSAID (Diclofenac sodium). Upper GI endoscopy done twice did not reveal any abnormality. Upper gastrointestinal (UGI) barium series with small bowel follow through revealed a diverticulum on medial wall of second part of duodenum and there was evidence of ulce...
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Non-steriodal anti-inflammatory drugs (NSAID) are not only associated with bleeding in the stomach and duodenum, but can also complicate pre-existing diverticular disease of the colon. Here, a 58 year-old male with severe per rectal bleeding is presented and the role of NSAID as a causative factor of his problem is discussed.
متن کاملACP Journal Club. Review: New oral anticoagulants added to antiplatelets reduce CV events but increase bleeding after ACS.
New oral anticoagulants in addition to single or dual antiplatelet therapy after an acute coronary syndrome: a systematic review and meta-analysis. Eur Heart J. 2013 Mar 6. [Epub ahead of print] Commentary Contemporary, evidence-based care calls for lifelong aspirin therapy after an ACS and up to 12 months of dual APT after percu-taneous coronary intervention (PCI). Although the use of new oral...
متن کاملNewer Antiplatelets
Many therapeutic drugs have been identified that possess clinically important antiplatelet activity. Platelet inhibition can be achieved in numerous ways (Fig. 1), including inhibition of platelet cyclooxygenase, inhibition of ADP receptors or inhibition of the platelet glycoprotein (GP) IIb/ IIIa receptor. Pharmacological inhibition of platelet function can also be achieved by interference wit...
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ژورنال
عنوان ژورنال: Korean Journal of Clinical Pharmacy
سال: 2018
ISSN: 1226-6051,2508-786X
DOI: 10.24304/kjcp.2018.28.3.250